Carboxymethyl-beta-cyclodextrin sodium salt
Product Name: Carboxymethyl-Beta-cyclodextrin sodium salt
Cas No: 218269-34-2
Synonyms:
CARBOXYMETHYL BETA-CYCLODEXTRIN;Carboxymethyl-beta-cyclodextrin sodium salt;carboxymethylated-beta-cyclodextrin;CM-B-CD
Structural Formula: Carboxymethyl-β-cyclodextrin sodium salt
Molecular Formula: C42H70-nO35·(CH2COONa)n
Molecular Weight: 1135.0+80n
Appearance:white powder
Assay:>=98%
Application
In solution that pH<4, carboxymethyl-β-cyclodextrin (CM-β-CD) solubility is low. But in pH>4 solution that carboxyl group dissociate, CM-β-CD can dissolved in water in any concentration. It has a good solubility in the human intestinal environment that pH is 6-7. CM-β-CD that has lower hemolysis than HP-β-CD can be used in prolonged release formulations.
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